Wonderful bronchodilatory indigenous plant (adhatoda vasica): A phyto-pharmacological profile
Mohammad Abu Bin Nyeem, Mustofa Nabi, BM Rabiul Islam, Md. Moksed Ali, Sanjeeda Sultana, Rabeya Siddika
Adhatoda vasica Linn belongs to the family of Acanthaceae, commonly known as Basok is a well-known herb in indigenous systems of medicine for its bronchodilatory effects. The aim of the present study was to evaluate the update data on phytochemical compositions and pharmacological properties of different parts of Adhatoda vasica are reviewed. Adhatoda has been used for a variety of disorders including cold, cough, bronchitis, asthma, thirst, fever, vomiting, loss of memory, tumors, and mouth troubles. Adhatoda vasica L. also has anti-tubercular, anti-allergic, anti-asthmatic, anti-inflammatory, hepatoprotective, anthelmintic, antimicrobial, wound healing, anti-ulcer, antibacterial, antihistaminic, antimutagenic, uterotonic and abortifacient activities. This plant contains alkaloids, tannins, flavonoids, terpenes, and glucosides. The principle constituents of Adhatoda are its several alkaloids, the chief one being vasicine. The leaves contain two major alkaloids called vasicine and vasicinone. The leaves of Adhatoda are rich in vitamin C, carotene and essential oil. The roots are known to contain vasicinolone, vasicol, peganine, sitosterol, β-glucoside-galactose and deoxyvasicine and 2'hydroxy-4- glucosyl-oxychalcone. The flowers contain b-sitosterol-D-glucoside, kaempferol, its glycosides and quercetin, adhatonine, vasinol.